Spider-Man is about growing up. And the problem with a married Spidey boils down to the fact that, at that point, he's not growing up any more--he's grown.This is a convenient rational but it isn't true. In many ways Peter Parker grew up in his first couple of appearances. From there it's been about responsibility. Spider-Man stories have never been about growing up. Yes, Peter has grown over the years. So have all of the younger Marvel characters (even Rick Jones).
Peter spent years complaining about the "Parker luck" - a complaint that has resurfaced. Back before this was a retro complaint Peter's real problem was that he was trying to do too much. The second movie touched on this same theme. Peter's personal life was a mess because he kept putting other people first. If he gave up helping other people then he got his own life together but other people got hurt.
But the powers that be have decided that Spider-Man is about growing up. At the same time, he will not actually grow up. Sort of pointless, isn't it.
This actually describes a different Peter - Peter Pan, the boy who never grew up. In the book, Peter constantly forgot things and was, therefore constantly surprised (and hurt) by eperiences that were new to him.
The whole thing reminds me of post-Crisis Superman. I read it for a while but I never felt that it was really my Superman. It was a different guy in the same suit. He was nice enough but he just wasn't the real Superman. The new Spider-Man is the same thing. He is a Spider-Man but not the real Spider-Man.
One ray of hope - one of the comments speculated that this is all part of the countdown to issue 600 and that this will be undone, also.